Antioxidant and antimicrobial evaluation of the methanol leaf extract and fractions of dacryodes klaineana pierre (burseraceae)
نویسندگان
چکیده
ABSTRACT. Dacryodes klaineana is used in traditional medicine for the treatment of painful menstruation; tachycardia and cough. The study aims to evaluate antioxidant antimicrobial properties plant. extract fractions D. were screened their effects using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing power (FRAP), total phenolic contents (TPC) assay methods. activity plant was evaluated agar diffusion method against four different bacterialstrains (Staphylococcus aureus, Bacillus subtilis, Escherichia coli Pseudomonas aeruginosa) two fungi strains (Aspergillus niger Candida albicans). crude methanol (MLE), hexane fraction (MLHF), ethyl acetate (MLEF) butanol (MLBF) produced dose-dependent DPPH FRAP assays. MLEF comparable standard drug, ascorbic acid. also gave highest content phenol with a percent gallic acid equivalent 100.68 ± 1.17 mg GAE/g. active bacteria species, but inactive species. demonstrated that potentials may offer promising source new antioxidants antimicrobials ethnomedicinal management diseases.
 
 KEY WORDS: Medicinal plant, FRAP, TPC, DPPH, Antioxidant, klaineana
 Bull. Chem. Soc. Ethiop. 2022, 36(1), 85-94. DOI: https://dx.doi.org/10.4314/bcse.v36i1.8
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ژورنال
عنوان ژورنال: Bulletin of The Chemical Society of Ethiopia
سال: 2022
ISSN: ['1011-3924', '1726-801X']
DOI: https://doi.org/10.4314/bcse.v36i1.8